General Information

  • ID:  hor000351
  • Uniprot ID:  A0A1S4FV87
  • Protein name:  MIP-3
  • Gene name:  NA
  • Organism:  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  VNAGPAQWNKFRGSW
  • Length:  15(148-162)
  • Propeptide:  MINQHLILWTNFGKLLLLLVLCSLVSNIQTESASLEQHQMEHADESTHSHSPQKRTWKNLQGGWGKRTPTSEQPDPNADYYGYTGRNDDTADYGNAENELDKLNKYLIKGLINQRLAQLDTQYDGSDEEYPVEKRAWNKINGGWGKRVNAGPAQWNKFRGSWGKREPGWNNLKGLWGKRSEKWNKLSSSWGKRDSGNSNSY
  • Signal peptide:  MINQHLILWTNFGKLLLLLVLCSLVSNIQT
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000351_AF2.pdbhor000351_ESM.pdb

Physical Information

Mass: 196780 Formula: C79H112N24O20
Absent amino acids: CDEHILMTY Common amino acids: AGNW
pI: 11.65 Basic residues: 2
Polar residues: 5 Hydrophobic residues: 6
Hydrophobicity: -88.67 Boman Index: -2551
Half-Life: 100 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 32.67
Instability Index: 4052.67 Extinction Coefficient cystines: 11000
Absorbance 280nm: 785.71

Literature

  • PubMed ID:  20163154
  • Title:  Neuropeptidomics of the Mosquito Aedes Aegypti